We describe the dynamics for a system of screw dislocations subject to anti-plane shear. Variational techniques allow us to find minimizers for the energy functional associated with the system of dislocations in an elastic medium. Building on a model due to Cermelli and Gurtin, a weak notion of solutions (in the sense of Filippov) to ordinary differential equations is used to solve the dynamics problem. Some examples of interesting scenarios complement the presentation.
Michael Köpf (École Normale Supérieure, Paris, France)
A continuum model of wound healing in epithelial tissues
During unconstrained spreading as occurs for example in wound healing, epithelial cell monolayers can be described as a polarizable and chemo-mechanically interacting layer with weakly nonlinear elasticity. Our model reproduces the spontaneous and self-organized formation of finger-like protrusions due to the collective action of a large number of cells, that is commonly observed in experiments. Statistics of the velocity orientation obtained from numerical simulation show strong alignment in the fingers opposed to an isotropic distribution in the bulk, in good agreement with the measurements by Reffay et al. (Reffay et al., Biophysical Journal, 2011). The results faithfully reproduce faster relative advance of cells close to the leading edge of the tissue, as well as spatial velocity correlations and stress accumulation within the tissue, which proceeds in form of a "mechanical wave", travelling from the wound edge inwards (cf. Serra-Picamal et al., Nature Physics, 2012).
M. H. Koepf, L. M. Pismen: Non-equilibrium patterns in polarizable active layers, Physica D 259 (2013) 48-54
M. H. Koepf, L. M. Pismen: A continuum model of epithelial spreading, Soft Matter 9 (2013) 3727-3734
Dirk Peschka (WIAS Berlin)
Treatment of triple junctions in thin-film models
joint work with R. Huth, S. Jachalski and G. Kitavtsev
Stokes free boundary problems have a gradient flow structure which determines conditions at boundaries and in particular at triple junctions (liquid/substrate/gas). The same structure carries over to corresponding dimensionally reduced thin-film models. In order to devise a numerical algorithm we discuss the weak-form of the gradient flow and discuss different ways to treat the motion of compactly supported liquid films with nonzero contact angle, e.g. droplets. We indicate how this method can be generalised to multi-layered systems of thin-films and demonstrate the feasibility of the approach by presenting a few numerical solutions in 2D and 3D.
Filip Rindler (U Warwick)
Orientation-preserving Young measures
Young measures are widely used in the Calculus of Variations to model limits of nonlinear functions of weakly converging "generating" sequences. Often, one is interested in special classes of Young measures that are generated by constrained sequences (e.g. gradients or divergence-free vector fields). After introducing Young measures, I will outline the proof of a recent characterization result (in the spirit of the Kinderlehrer--Pedregal Theorem) for Young measures generated by gradients that have positive Jacobian almost everywhere. The argument to construct generating sequences from such Young measures satisfying the orientation-preserving constraint is based on a variant of convex integration in conjunction with an explicit lamination construction in matrix space. The resulting generating sequence is bounded in $\Lrm^p$ for $p$ less than the space dimension. Applications to relaxation of integral functionals, the theory of semiconvex hulls, and approximation of weakly orientation-preserving maps by strictly orientation-preserving ones in Sobolev spaces are given.
Hao Wu (Fudan U)
Well-posedness and stability of the full Ericksen-Leslie system for incompressible nematic liquid crystal flow
We will discuss the Ericksen-Leslie (E-L) system modeling the incompressible nematic liquid crystal flow. We prove the well-posedness and long-time behavior of the E-L system under proper assumptions on the viscous Leslie coefficients. We also discuss the connection between Parodi's relation and stability of the E-L system.
CONTRIBUTED TALKS
Vladimir Bobkov (Ufa Science Center, RAS)
On the behaviour of branch of gound state solutions to the system of elliptic equations
We consider the behaviour of solutions to the system of elliptic equations with indefinite nonlinearity depending on two spectral parameters. We introduce a curve of critical spectral points, which is the threshold of applicability of the Nehari manifolds and fibering methods. A branch of ground state is obtained and its asymptotic behavior including the blow-up phenomenon on the critical curve is studied. The differences in the behavior of similar branches of solutions for the prototype scalar equations are discussed
Karoline Disser (WIAS Berlin)
On gradient structures for Markov chains and the passage to Wasserstein gradient flows
We prove the convergence of the gradient structure for a spatially discrete reversible Markov chain introduced in [3] and [2] to the Wasserstein gradient structure of the linear Fokker-Planck equation, complementing and partially extending the results in [1].
References
[1] Nicola Gigli and Jan Maas, Gromov-Hausdorff convergence of discrete transportation metrics, SIAM J. Math. Anal. 45 (2013), no. 2, 879--899.
[2] Jan Maas, Gradient flows of the entropy for finite Markov chains, J. Funct.Anal. 261 (2011), no. 8, 2250--2292.
[3] Alexander Mielke, Geodesic convexity of the relative entropy in reversible Markov chains, Calc. Var. Partial Differential Equations 48 (2013), no. 1-2,1--31. MR 3090532
Svetlana Gurevich (Münster U)
Delayed feedback control of localized structures in reaction-diffusion systems
We are interested in stability properties of a single localized structure in a three-component reaction-diffusion system subjected to the time-delayed feedback. We shall show that variation in the product of the delay time and the feedback strength leads to complex dynamical behavior of the system, including formation of target patterns, spontaneous motion, and spontaneous breathing as well as various complex structures, arising from combination of different oscillatory instabilities. In the case of spontaneous motion, we provide a bifurcation analysis of the delayed system and derive an order parameter equation for the position of the localized structure, explicitly describing its temporal evolution in the vicinity of the bifurcation point. This equation is a subject to a nonlinear delay differential equation, which can be transformed to the normal form of the pitchfork drift bifurcation.
Patrick van Meurs (Eindhoven U Tech.)
Collective Behaviour of Walls of Dislocations
We address a scientific challenge occurring in many complex systems: predicting the evolution of the collective behaviour of particles interacting on the micro scale. More specifically, we examine dislocation networks, which have plastic deformation of metals as the emergent property. There are many dislocations in metals, and every dislocation interacts with all the others in a non-local way. The main challenge is to do upscaling (the number of dislocations goes to infinity). I will present to you how we did this in a variational framework for the static case, which is the first step towards treating dynamics.
Elias Pipping (FU Berlin)
Variational methods for rate- and state-dependent friction problems.
In geophysics, there is a need for friction laws with the property that an increase in the sliding velocity $V$ yields a decrease in the friction coefficient $\mu$, i.e. a decrease in frictional resistance. Unfortunately, a straightforward formulation, i.e. $\mu = \mu(V)$ leads to physical absurdities and mathematical issues (both on the computational and the analytical level, because of a lack of monotonicity). This model is referred to as (slip) ratedependent friction. A more complicated, experiment-based model, in which an increase in velocity first leads to an increase in velocity, and then (after a finite amount of time) an overall decrease, does not have these shortcomings. The time-delay effect is incorporated into the formulation through a state variable $\theta$, yielding $\mu = \mu(V, \theta)$; hence the name (slip) rate- and state-dependent friction.
In this presentation I will talk about how variational methods help us in solving problems of rate- and state-dependent friction and where the remaining challenges are.
Sina Reichelt (WIAS Berlin)
Two-scale homogenization in nonlinear reaction-diffusion systems with small diffusion
Alexander Mielke, Sina Reichelt*, and Marita Thomas
Many reaction-diffusion processes arising in civil engineering, biology, or chemistry take place in media with underlying microstructure, for instance concrete carbonation or the spread-out of substances in biological tissues. Such microstructures are assumed to be periodically distributed with period length $\varepsilon > 0$, which is much smaller compared to the overall size of the domain. Systems with such differences in the involved length scales are very difficult to handle numerically, because the step size of the algorithm has to be of order $\varepsilon$ in order to resolve the qualitative behavior of the system. Therefore it is the aim to derive effective equations, independent of $\varepsilon$, which are ideally simpler and qualitatively describe the properties of the original system. In the classical case, the coffecients in the effective equation are homogeneous and in this sense, the passage $\varepsilon \to 0$ is called homogenization.
In my talk I deal with a system of two coupled reaction-diffusion equations, where one species diffuses much slower than the other one and the coupling arises via nonlinear reaction terms. Using the method of two-scale convergence, I derive effective equations which are defined on a two-scale space. The two-scale space consists of the macroscopic domain and the microscopic unit cell attached to each point of the macroscopic domain.
Fabian Spill (Oxford U)
Modelling of Angiogenesis
Angiogenesis is the formation of new blood vessels from existing ones. It is a crucial process occurring in wound healing or in solid tumours. As the tumour needs to induce angiogenesis to be able to grow beyond a limited size, much medical research has been directed towards targeting angiogenesis. In this talk, I will review different approaches to the modelling of angiogenesis, such as PDE models which describe the global evolution of observable cell densities, stochastic models describing individual cells, or multiscale models.
Giles Shaw (Cambridge U)
Continuous Extension of Integral Functionals over W^{1,1}.
In this talk, I will identify the area-strictly continuous extension of integral functionals defined on W^{1,1} to the space BV. Here, the integrand of the functional depends on the spatial domain as well as u(x) and \nabla u(x). This result is complementary to a work of Amar, De Ciccio and Fusco [ESAIM Control Optim. Calc. Var. 13 (2007), no. 2, pp. 396–412], but is valid for vector valued functions u(x) as well as just the scalar case. The main point is that, when a jump point of a BV function is encountered, the integrand must be averaged across all values between the upper and lower limits at the jump point.
Miguel Yangari (U Toulouse)
Fast propagation for fractional kpp equations with slowly decaying initial conditions.
In this talk, I present a study about the large-time behavior of solutions of one-dimensional fractional Fisher-KPP reaction-diffusion equations, when the initial condition is asymptotically frontlike and it decays at infinity more slowly than a power x^b, where b < 2α and α∈(0,1) is the order of the fractional Laplacian. We prove that the level sets of the solutions move exponentially fast as time goes to infinity. Moreover, a quantitative estimate of motion of the level sets is obtained in terms of the decay of the initial condition.
Markus Wilczek (Münster U)
Synchronization effects in Cahn-Hilliard models for Langmuir-Blodgett transfer
The pattern formation in Langmuir-Blodgett transfer experiments is theoretically studied using a generalized Cahn-Hilliard model. The influence of prestructured substrates on the patterning process is investigated in one and two dimensions. We find that the occurring synchronization effects enable a control mechanism via properties of the prestructure and facilitate the production of patterns with a broader range of features. In two dimensions, the production of a variety of complex patterns can be achieved through the competition of intrinsic properties of the pattern forming system and the external forcing introduced by a prestructure.
Martijn Zaal (Bonn U)
Variational modeling of osmotic cell swelling
A variational formulation of a class of parabolic free boundary problems is given. An example of such a problem is the swelling of a single cell due to osmosis. The variational formulation is used to show global existence of solutions.